Aspirin:
• only agent established as effective for early treatment of acute ischemic stroke.
• Should be given asap if no bleed
• No Aspirin after tpa for 24 hour
For Asian patients with high-risk TIA or minor stroke (ie, NIHSS score < 3)
= Consider dual antiplatelet treatment, rather than aspirin alone
- clopidogrel (300 mg loading dose, then 75 mg daily) plus aspirin (75 to 300 mg loading dose, then 75 to 81 mg daily) for 21 days
- - followed by clopidogrel monotherapy (75 mg daily) through at least day 90
After the acute phase of ischemic stroke and TIA, long-term antiplatelet therapy for secondary stroke prevention
= aspirin or
= clopidogrel 75 mg qd (Plavix) (<$10 for 30) or
= aspirin with extended-release dipyridamole 25/200 mg bid (generic cost $130 for 60 cap)
Index