Lower extremity neuropathy
Quick synopsis
bulletMeralgia paresthetica: numb anterior lateral thigh, no motor weakness.
bulletFemoral neuropathy: diabetic amyotrophy, retroperitoneal/pelvic hematoma, tumor. Weak iliopsoas and quadriceps, numb anterior medial thigh down to medial malleolus.
bulletPeroneal neuropathy: trauma at fibular neck. Weak dorsiflexion, inversion and eversion of ankle. Numb dorsum of foot.
bulletObturator neuropathy: caused by pelvic neoplasm and surgery, pregnancy. Pain at medial thigh, weak hip adduction.
Nerve History, Exam & Common Etiology
Femoral -  Saphenous
bulletHistory: leg weakness on attempt to stand
bulletMotor: quadriceps weakness
bulletSensory: anterior medial thigh down to medial malleolus.
bulletDTR: decreased Knee reflex
bulletCauses:
bulletSurgical trauma: intrapelvic, inguinal, hip operations
bulletStretch or traction injury
bulletDirect compression in Iliacus compartment
Saphenous
bulletHistory: may go unnoticed or complains of burning pain at  medial lower leg
bulletMotor: normal
bulletSensory:  medial lower leg loss
bulletCauses: Surgical or other injury over the knee or medial lower leg: arterial surgery, Saphenous vein removal, knee operation
Obturator
bulletHistory: Leg weakness
bulletMotor: hip adduction weakness
bulletSensory: upper medial thigh
bulletIsolated involvement uncommon
bulletCauses: hip or pelvic fracture, other nerves usually involved. Pelvic mass
Iliohypogastric, Ilioinguinal, Genitofemoral
bulletHistory: pain, burning over inguinal & Perineal area
bulletMotor: normal
bulletSensory loss:
bulletIliohypogastric: suprapubic, upper buttock area
bulletIlioinguinal: inguinal and base of genitalia
bulletGenitofemoral: medial & proximal genitalia
bulletCause: surgical procedure: especially inguinal herniorrhaphy
Lateral femoral cutaneous (Meralgia paresthetica)
bulletHistory: pain, burning over anterolateral thigh
bulletMotor: normal
bulletSensory: limited sensory loss over the lateral thigh
bulletCommon causes: entrapment at lateral inguinal ligament, rarely from retroperitoneal lesion.
Sciatic
bulletHistory: complete lesion infrequent, lateral trunk (Peroneal) more commonly involved
bulletMotor: weakness of hamstrings and all muscles below the knee
bulletSensory loss variable: distribution of Peroneal & Tibial nerve
bulletCommon causes:
bulletPelvic, hip or femur fracture
bulletCompression injury from prolonged immobility
bulletEntrapment by fibrous band, local hematoma, tumor
Peroneal
bulletHistory: Foot drop
bulletMotor: weakness of ankle dorsiflexion, eversion, inversion and toe extension.
bulletSensory loss over anterolateral lower leg, dorsum of foot & toes
bulletCauses:
bulletExternal compression: pressure, cast
bulletExternal trauma: blunt injury, knee surgery & fracture
bulletTraction injury: severe ankle sprain
Tibial
bulletHistory: numbness along the side of foot
bulletMotor: weakness in toe flexor, if more proximal portion is involved, ankle inversion weakness
bulletSensory loss: sole of the foot
bulletRarely seen.
bulletCommon cause: usually caused by severe ankle injury
Medial & lateral plantar (Tarsal tunnel syndrome)
bulletHistory: foot pain is more commonly from orthopedic origin.
bulletMotor: may have weakness in toe flexor
bulletSensory loss in toes
bulletCommon cause: external compression or ankle injury
Pudendal
bulletFecal & urinary incontinence
bulletSensory loss over perineum
bulletCommon cause: prolonged labor
Further reading & review
bulletInnervation of lower extremity muscles - Washington Univ
bulletReview of cutaneous field of peripheral nerves
bulletSpinal root syndromes - UNC
bulletCervical, lumbar plexus & peripheral nerves - Memorial Univ of Newfoundland - Canada
bulletSports induced inflammation in the LE - Hosp Practice Feb 99

 

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