| Lower extremity
neuropathy |
| Quick synopsis |
 | Meralgia paresthetica: numb anterior lateral
thigh, no motor weakness. |
 | Femoral neuropathy: diabetic amyotrophy,
retroperitoneal/pelvic hematoma, tumor. Weak iliopsoas and quadriceps,
numb anterior medial thigh down to medial malleolus. |
 | Peroneal neuropathy: trauma at fibular neck. Weak
dorsiflexion, inversion and eversion of ankle. Numb dorsum of foot. |
 | Obturator neuropathy: caused by pelvic neoplasm
and surgery, pregnancy. Pain at medial thigh, weak hip adduction. |
|
| Nerve |
History, Exam & Common Etiology |
Femoral - Saphenous
|
 | History: leg weakness on attempt to stand |
 | Motor: quadriceps weakness |
 | Sensory: anterior
medial thigh down to medial malleolus. |
 | DTR: decreased Knee reflex |
 | Causes:
 | Surgical trauma: intrapelvic, inguinal, hip operations |
 | Stretch or traction injury |
 | Direct compression in Iliacus compartment |
|
|
| Saphenous |
 | History: may go unnoticed or complains of burning pain at medial
lower leg |
 | Motor: normal |
 | Sensory: medial lower leg loss |
 | Causes: Surgical or other injury over the knee or medial lower leg:
arterial surgery, Saphenous vein removal, knee operation |
|
| Obturator |
 | History: Leg weakness |
 | Motor: hip adduction weakness |
 | Sensory: upper medial thigh |
 | Isolated involvement uncommon |
 | Causes: hip or pelvic fracture, other nerves usually involved. Pelvic
mass |
|
| Iliohypogastric, Ilioinguinal, Genitofemoral |
 | History: pain, burning over inguinal & Perineal area |
 | Motor: normal |
 | Sensory loss:
 | Iliohypogastric: suprapubic, upper buttock area |
 | Ilioinguinal: inguinal and base of genitalia |
 | Genitofemoral: medial & proximal genitalia |
|
 | Cause: surgical procedure: especially inguinal herniorrhaphy |
|
| Lateral femoral cutaneous (Meralgia
paresthetica) |
 | History: pain, burning over anterolateral thigh |
 | Motor: normal |
 | Sensory: limited sensory loss over the lateral thigh |
 | Common causes: entrapment at lateral inguinal ligament, rarely from
retroperitoneal lesion. |
|
Sciatic
|
 | History: complete lesion infrequent, lateral trunk (Peroneal) more
commonly involved |
 | Motor: weakness of hamstrings and all muscles below the knee |
 | Sensory loss variable: distribution of Peroneal & Tibial nerve |
 | Common causes:
 | Pelvic, hip or femur fracture |
 | Compression injury from prolonged immobility |
 | Entrapment by fibrous band, local hematoma, tumor |
|
|
Peroneal
|
 | History: Foot drop |
 | Motor: weakness of ankle dorsiflexion, eversion,
inversion and toe extension. |
 | Sensory loss over anterolateral lower leg, dorsum of foot & toes |
 | Causes:
 | External compression: pressure, cast |
 | External trauma: blunt injury, knee surgery & fracture |
 | Traction injury: severe ankle sprain |
|
|
Tibial
|
 | History: numbness along the side of foot |
 | Motor: weakness in toe flexor, if more proximal portion is involved,
ankle inversion weakness |
 | Sensory loss: sole of the foot |
 | Rarely seen. |
 | Common cause: usually caused by severe ankle injury |
|
Medial & lateral plantar (Tarsal tunnel syndrome)
|
 | History: foot pain is more commonly from orthopedic origin.
|
 | Motor: may have weakness in toe flexor |
 | Sensory loss in toes |
 | Common cause: external compression or ankle injury |
|
| Pudendal |
 | Fecal & urinary incontinence |
 | Sensory loss over perineum |
 | Common cause: prolonged labor |
|
| Further reading & review
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