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Opioid Analgesics for adults Class II

bullettitrate to individual response
bulletdose does not apply to patients with renal or hepatic insufficiency
bulletMorphine
bulletImmediate release (MSIR): tab 15, 30 mg. Dose: 5-30 mg q2-6h
bulletMS Contin, Oramorph SR: Tab: 15, 30, 60, 100 mg. Dose 15-120 mg q12
bulletRoxanol SR: 30 mg. Dose 30 mg q8 prn
bulletUsual parenteral dose: 5-10 mg q4-5h
bulletHydromorphone (Dilaudid)
bulletTab: 2, 4, 8 mg. Dose: 2-6 mg po q3-4h
bullet 3 mg rectal suppository
bulletUsual parental dose: 1.5 mg q3-4h
bulletLevorphanol (Levo-Dromoran)
bulletOral: 4 mg q6-8h
bulletUsual parental dose: 2 mg q6-8h
bulletMeperidine (Demerol)
bulletOral dose not recommended
bulletUsual parenteral dose: 50-100 mg q3h, extreme caution if patient has renal failure, accumulation of active metabolite may cause CNS excitement & seizure
bulletMethadone (Dolophine)
bulletOral: 5-20 mg q6-8h
bulletUsual parenteral dose: 10 mg q6-8h
bulletOxycodone
bulletRoxicodone: soln: 5 mg/5ml, 20 mg/ml, tab 5 mg. Dose: 5-10 mg q3-4h
bullet Oxycontin controlled release tab: 10, 20 , 40 mg. Dose variable
bulletParenteral: not available
bulletOxymorphone (Numorphan)
bulletOral: not available
bulletUsual parenteral dose: 1 mg q3-4h
Further Reading
bulletIdentification and Management of the Drug-Seeking Patient - AFP May 2000
bulletNon opiod analgesics
bullet Opiod analgesics class III & IV
bullet Muscle relaxants

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